The dr.g dermoisture range is fantastic. It's perfect to soothe my skin when I use tretinoin. I was in search for a moisturizer before the tretinoin (sandwich) and I this do the job perfectly. When I use it together with tretinoin it worked perfectly. It's the best soothing and restoring lotion. My skin is very dry form the tretinoin so I use the balm of the same line after it. My sensitive and very dry skin never felt better. My method is: first the lotion then the tretinoin and then the cream or the blam from the same range.