These little hydrocolloid patches are so convenient!  The fluid needs a way to get out of the pore, so they're perfect for a blemish that has been lanced or which has ruptured on its own. Make sure to dab the area clean of any oils or creams before applying; and press firmly to make sure it really adheres to the skin. If using a spot treatment like benzoyl peroxide, make sure it dries BEFORE applying patch. Excellent overnight to reduce inflammation by morning.